⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177599 | 0.98 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL7994825 | 0.98 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL7994828 | 0.98 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL61666 | 0.93 | — | — | |
| SCHEMBL4333124 | 0.86 | ALDH1A1 (0.44) | — | |
| SCHEMBL4325752 | 0.85 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL7991224 | 0.85 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL791252 | 0.85 | ALDH1A1 (0.43) | — | |
| SCHEMBL7991219 | 0.85 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL4337073 | 0.83 | SMN1; SMN2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256299-A1 | 7-MORPHOLINO-5-(3-PHENYL-1 H-PYRAZOL-1 -YL)-FURO[3,2-B]PYRIDINE DERIVATIVES AND SIMILAR COMPOUNDS AS PIKFYVE KINASE INHIBITORS FOR THE TREATMENT OF E.G. AMYOTROPHIC LATERAL SCLEROSIS (ALS) | Verge Analytics, Inc. (US) | 2022-12-08 | — | — | WO | claimed |
| US-20090105482-A1 | Urea Glucokinase Activators | NOVO NORDISK A/S (DK) | 2009-04-23 | — | — | US | claimed |
| JP-2009501198-A | — | — | 2009-01-15 | — | — | JP | claimed |
| CN-101263131-A | Urea glucokinase activators | NOVO NORDISK AS (US) | 2008-09-10 | — | — | CN | claimed |
| EP-1904467-A1 | UREA GLUCOKINASE ACTIVATORS | Novo Nordisk A/S (DK) | 2008-04-02 | — | — | EP | claimed |
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | claimed |
| EP-3831325-B1 | SURGICAL ELECTRODE HAVING SURFACE TREATMENT COATING | NIHON PARKERIZING (JP) | 2024-06-05 | — | — | EP | disclosed |
| EP-4368750-A1 | METHOD FOR PRODUCING POLYOXYALKYLENE ALKYL ETHER ACETATE | Kao Corporation (JP) | 2024-05-15 | — | — | EP | disclosed |
| WO-2024075524-A1 | SURFACE TREATMENT AGENT FOR CARBON STEEL MATERIAL, AND CARBON STEEL MATERIAL WITH SURFACE TREATMENT COATING FILM AND PRODUCTION METHOD THEREOF | 日本パーカライジング株式会社 | 2024-04-11 | — | — | WO | disclosed |
| CN-117716054-A | Heat treatment oil composition | 出光兴产株式会社 | 2024-03-15 | — | — | CN | disclosed |
| EP-4331679-A2 | COMPOUNDS THAT INTERACT WITH THE RAS SUPERFAMILY FOR THE TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | Shy Therapeutics LLC (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117597472-A | Method for producing polyoxyalkylene alkyl ether acetic acid | 花王株式会社 | 2024-02-23 | — | — | CN | disclosed |
| CN-117480235-A | Heat treatment oil composition | 出光兴产株式会社 | 2024-01-30 | — | — | CN | disclosed |
| US-4622418-A | LOW CALORIE SWEETENERS | GENERAL FOODS CORPORATION (US) | 1986-11-11 | — | — | US | disclosed |
| US-4619782-A | L-aminodicarboxylic acid gem-diamines | GENERAL FOODS CORPORATION (US) | 1986-10-28 | — | — | US | disclosed |
| US-4572799-A | L-Aminodicarboxylic acid amides | GENERAL FOODS CORPORATION (US) | 1986-02-25 | — | — | US | disclosed |
| US-4282171-A | Phosphorus and sulfur containing amides and thioamides | THE LUBRIZOL CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4208357-A | Process for preparing phosphorus and sulfur containing amides and thioamides | THE LUBRIZOL CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4032461-A | PHOSPHORUS AND SULFUR CONTAINING AMIDES AND THIOAMIDES AS LUBRICATING OIL ADDITIVES AND LUBRICATING OIL COMPOSITIONS CONTAINING SAME | THE LUBRIZOL CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
| US-4031023-A | Lubricating compositions and methods utilizing hydroxy thioethers | THE LUBRIZOL CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |