Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880231 | 0.85 | KDM1A (0.42) | EPHX2KDM4EHDAC6ALDH1A1RAB9A | |
| SCHEMBL6879117 | 0.74 | EPHX2 (0.35) | EPHX2MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1758674 | 0.74 | HDAC6 (0.52) | EPHX2HDAC6KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6878384 | 0.74 | HDAC1 (0.44) | KDM4EHDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL6878631 | 0.74 | EPHX2 (0.42) | EPHX2MAPTCYP4F2CYP4A11KMT2A | |
| SCHEMBL6880270 | 0.73 | HDAC6 (0.50) | EPHX2KDM4EHDAC6KMT2AALDH1A1 | |
| SCHEMBL20535207 | 0.73 | ALDH1A1 (0.53) | EPHX2HDAC6CYP4F2CYP4A11KMT2A | |
| SCHEMBL6878370 | 0.73 | MEP1B (0.40) | EPHX2MAPTKMT2AALDH1A1RAB9A | |
| SCHEMBL18662245 | 0.68 | KMT2A (0.52) | KMT2ACXCR4 | |
| SCHEMBL20534925 | 0.67 | HDAC6 (0.73) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |