Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | IARS1 | P41252 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156493 | 0.90 | TBXAS1 (0.41) | HSD11B1LTB4RLTB4R2PPARGPPARA | |
| SCHEMBL6886057 | 0.86 | CYP4F2 (0.39) | KDM4EALDH1A1HPGDHDAC1HDAC8 | |
| SCHEMBL6156458 | 0.84 | HMGCR (0.40) | KDM4EALDH1A1HPGDHSD11B1PTPN1 | |
| SCHEMBL6158244 | 0.76 | PPARA (0.39) | PPARGPPARA | |
| SCHEMBL6887533 | 0.74 | HDAC1 (0.40) | KDM4EALDH1A1HDAC1HDAC8LTB4R | |
| SCHEMBL6887538 | 0.74 | HDAC1 (0.40) | KDM4EALDH1A1HDAC1HDAC8LTB4R | |
| SCHEMBL10698849 | 0.72 | PTGER2 (0.46) | PPARGPPARA | |
| SCHEMBL6885033 | 0.71 | PPARG (0.39) | KDM4EALDH1A1HDAC1HDAC8CYP4F2 | |
| SCHEMBL6885040 | 0.71 | PPARG (0.39) | KDM4EALDH1A1HDAC1HDAC8CYP4F2 | |
| SCHEMBL6154774 | 0.70 | HMGCR (0.50) | KDM4EALDH1A1HPGDHSD11B1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |