SCHEMBL687974

SCHEMBL687974

CCOC(=O)C(CC)=C(CC)CP(=O)(O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
SOAT1 P35610 1/20 0.35
ALDH1A1 P00352 4/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GLO1 Q04760 1/20 0.33
TSHR P16473 2/20 0.32
LMNA P02545 2/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HSD17B10 Q99714 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9020915 1.00 CYP2D6 (0.42) CYP2D6CYP2C9CYP2C19SOAT1ALDH1A1
Butyric Acid SCHEMBL11237544 0.89 FFAR3 (0.38) CYP2D6CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL9678720 0.83 ENO1 (0.34) CYP2D6CYP2C9CYP2C19TSHRLMNA
SCHEMBL800030 0.82 SOAT1 (0.46) CYP2D6CYP2C9SOAT1ALDH1A1NPSR1
SCHEMBL29250921 0.81 CYP2C9 (0.42) CYP2D6CYP2C9CYP2C19SOAT1ALDH1A1
Ammonia Solution, Strong SCHEMBL11056611 0.80 SOAT1 (0.44) CYP2D6CYP2C9SOAT1ALDH1A1NPSR1
SCHEMBL6691893 0.80 SOAT1 (0.44) CYP2D6CYP2C9SOAT1ALDH1A1NPSR1
SCHEMBL5962754 0.76 MEN1 (0.42) TSHRLMNAMEN1HPGDBLM
SCHEMBL3903608 0.76 MEN1 (0.42) TSHRLMNAMEN1HPGDBLM
SCHEMBL17616389 0.76 SOAT1 (0.41) CYP2D6CYP2C9SOAT1ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2644612-B1 Method for producing sanshool TSUMURA & CO (JP) 2016-01-06 EP claimed
US-8877953-B2 Method for producing sanshool TSUMURA & CO. (JP) 2014-11-04 US claimed
US-20130261327-A1 METHOD FOR PRODUCING SANSHOOL TSUMURA & CO. (JP) 2013-10-03 US claimed
EP-2644612-A1 Method for producing sanshool TSUMURA & CO. (JP) 2013-10-02 EP claimed
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 EP disclosed
US-12435181-B2 Formulations capable of reacting with or removal of molecular oxygen LI SHENSHEN (US) 2025-10-07 US disclosed
US-20240217983-A1 GPR119 AGONISTS KALLYOPE, INC. 2024-07-04 US disclosed
CN-115996914-B Novel heterocyclic compound and salt thereof, and luminescent substrate composition 国立大学法人电气通信大学 2024-06-07 CN disclosed
US-20240158359-A1 HYDROLYSIS-RESISTANT ESTERS FOR DRUG AND IMAGING AGENT DELIVERY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-05-16 US disclosed
WO-2024102730-A1 LIPIDS AND NANOPARTICLE COMPOSITIONS FOR DELIVERING POLYNUCLEOTIDES ORNA THERAPEUTICS, INC. (US) 2024-05-16 WO disclosed
EP-4320129-A1 GPR119 AGONISTS Kallyope, Inc. (US) 2024-02-14 EP disclosed
US-4310545-A Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino) phenyl compounds AMERICAN CYANAMID COMPANY (US) 1982-01-12 US disclosed
US-4305959-A Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds AMERICAN CYANAMID COMPANY (US) 1981-12-15 US disclosed
US-4281019-A 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents AMERICAN CYANAMID COMPANY (US) 1981-07-28 US disclosed
US-4259352-A 4-[Cycloalkyl- or cycloalkenyl-amino(cycloalkyl- or cycloalkenyl-alkenyl)amino]phenyl compounds, useful as hypolipidemic and antiatherosclerotic agents AMERICAN CYANAMID COMPANY (US) 1981-03-31 US disclosed
US-4211783-A Hypolipidemic and antiatherosclerotic novel 4-(aralkyl- and heteroarylalkylamino)phenyl compounds AMERICAN CYANAMID COMPANY (US) 1980-07-08 US disclosed
US-4205085-A Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino)phenyl compounds AMERICAN CYANAMID COMPANY (US) 1980-05-27 US disclosed
EP-0003663-A2 Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-08-22 EP disclosed
US-4107188-A FOR DECREASING LIPID LEVELS HOFFMANN-LA ROCHE INC. (US) 1978-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130261327-A1 METHOD FOR PRODUCING SANSHOOL SCO2, FTH1, CNKSR1 CYP2D6 2937/4885CYP2C9 1646/4885CYP2C19 2716/4885
US-20240158359-A1 HYDROLYSIS-RESISTANT ESTERS FOR DRUG AND IMAGING AGENT DELIVERY ABCG2, BLVRB, CES1 CYP2D6 272/4885CYP2C9 259/4885CYP2C19 499/4885
US-20240217983-A1 GPR119 AGONISTS GPR119, GLP1R, GCGR CYP2D6 2317/4885CYP2C9 2350/4885CYP2C19 1407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.