Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332631 | 0.86 | KCNH2 (0.40) | HTR2ASIGMAR1POLBKCNH2DRD1 | |
| SCHEMBL6468704 | 0.84 | KCNH2 (0.45) | HTR2ASIGMAR1L3MBTL1BCL2L1KCNH2 | |
| SCHEMBL1900476 | 0.83 | TP53 (0.41) | HTR2AHRH1TP53CYP1A2CYP3A4 | |
| SCHEMBL677297 | 0.83 | LIPG (0.39) | TLR8CYP3A4CYP2C9BCL2L1KCNH2 | |
| SCHEMBL10894648 | 0.81 | KCNH2 (0.49) | LMNAHTR2ASIGMAR1TP53CYP3A4 | |
| SCHEMBL815623 | 0.81 | GABRA1 (0.34) | HTR2ACYP3A4CYP2C9POLBBCL2L1 | |
| SCHEMBL815763 | 0.81 | LIPG (0.34) | TLR8CYP3A4CYP2C9KCNH2 | |
| SCHEMBL721135 | 0.81 | CALM1 (0.44) | HTR2AHRH1CYP3A4L3MBTL1CALM1 | |
| SCHEMBL817104 | 0.80 | LIPG (0.44) | HTTTP53CYP3A4TSHRBCL2L1 | |
| SCHEMBL7267794 | 0.80 | LIPG (0.44) | HTTTP53CYP3A4TSHRBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242471-B1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-29 | — | — | EP | claimed |