Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL5841329 | 0.79 | TDP1 (0.47) | TDP1ALDH1A1GAAHPGDMAPT | |
| SCHEMBL7891555 | 0.78 | ALDH1A1 (0.54) | TDP1ALDH1A1GAAHPGDMAPT | |
| SCHEMBL715554 | 0.78 | ALDH1A1 (0.58) | TDP1ALDH1A1GAAHPGDMAPT | |
| SCHEMBL30081463 | 0.78 | ALDH1A1 (0.58) | TDP1ALDH1A1GAAHPGDMAPT | |
| SCHEMBL11109074 | 0.77 | ALDH1A1 (0.53) | TDP1ALDH1A1GAAHPGDMAPT | |
| SCHEMBL372264 | 0.77 | ALDH1A1 (0.62) | TDP1ALDH1A1GAAHPGDMAPT | |
| SCHEMBL6340621 | 0.77 | ALDH1A1 (0.53) | TDP1ALDH1A1GAAHPGDMAPT | |
| SCHEMBL807146 | 0.77 | TLR8 (0.55) | ALDH1A1GAAHPGDMAPTGLA | |
| SCHEMBL372183 | 0.77 | ALDH1A1 (0.53) | TDP1ALDH1A1GAAHPGDMAPT | |
| SCHEMBL29953988 | 0.77 | ALDH1A1 (0.53) | TDP1ALDH1A1GAAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699569-B1 | AMINOPYRIMIDINE KINASE INHIBITORS | JASCO PHARMACEUTICALS LLC (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2699569-B1 | AMINOPYRIMIDINE KINASE INHIBITORS | JASCO PHARMACEUTICALS LLC (US) | 2017-08-30 | — | — | EP | disclosed |
| CN-104650054-A | Antitubercular quinolylthienylaryloxyethylamine derivative | CHONGQING PHARM RES INST CO | 2015-05-27 | — | — | CN | disclosed |
| US-8901145-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901145-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901145-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| WO-2012145617-A9 | AMINOPYRIMIDINE KINASE INHIBITORS | Jasco Pharmaceuticals, LLC (US) | 2014-02-20 | — | — | WO | disclosed |
| WO-2012145617-A2 | AMINOPYRIMIDINE KINASE INHIBITORS | Jasco Pharmaceuticals, LLC (US) | 2012-10-26 | — | — | WO | disclosed |
| US-20120270892-A1 | Aminopyrimidine Kinase Inhibitors | Jasco Pharmaceuticals, LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120270892-A1 | Aminopyrimidine Kinase Inhibitors | Jasco Pharmaceuticals, LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120270892-A1 | Aminopyrimidine Kinase Inhibitors | Jasco Pharmaceuticals, LLC (US) | 2012-10-25 | — | — | US | disclosed |
| EP-1871782-B1 | DIPHOSPHINES AND METAL COMPLEXES | UMICORE AG & CO KG (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-7863447-B2 | Diphosphines and metal complexes | UMICORE AG & CO., KG (DE) | 2011-01-04 | — | — | US | disclosed |
| US-20090270622-A1 | Diphosphines and Metal Complexes | UMICORE AG & CO., KG (DE) | 2009-10-29 | — | — | US | disclosed |
| EP-1871782-A2 | DIPHOSPHINES AND METAL COMPLEXES | Umicore AG & Co. KG (DE) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006111535-A2 | DIPHOSPHINES AND METAL COMPLEXES | UMICORE AG & CO. KG (DE) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270622-A1 | Diphosphines and Metal Complexes | C9, AP3S1, C5 | TDP1 3700/4885ALDH1A1 4243/4885GAA 4864/4885 |
| US-20120270892-A1 | Aminopyrimidine Kinase Inhibitors | PIM1, PIM2, PIM3 | TDP1 1037/4885ALDH1A1 3305/4885GAA 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.