Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HAT1 | O14929 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6215593 | 0.82 | MKNK1 (0.50) | EP300HDAC4DHODHWNT3ARIPK1 | |
| SCHEMBL6854741 | 0.79 | EP300 (0.40) | EP300HDAC4DHODHCES1WNT3A | |
| SCHEMBL6874956 | 0.78 | CYP1A2 (0.49) | CES1FAAHLTA4HEPHX2CA2 | |
| SCHEMBL6878881 | 0.75 | EP300 (0.41) | EP300HDAC4DHODHCES1WNT3A | |
| SCHEMBL6852546 | 0.75 | WNT3A (0.42) | EP300HDAC4DHODHWNT3A | |
| SCHEMBL3118237 | 0.75 | CYP2A6 (0.50) | EP300HDAC4DHODHWNT3ALTA4H | |
| SCHEMBL13637169 | 0.75 | RAB9A (0.44) | HDAC4DHODHWNT3A | |
| SCHEMBL3118227 | 0.75 | HDAC4 (0.40) | EP300HDAC4DHODHWNT3A | |
| SCHEMBL3535251 | 0.73 | CA2 (0.54) | LTA4HEPHX2CA2CYP4A11 | |
| SCHEMBL6876121 | 0.73 | AOC3 (0.50) | EP300HDAC4DHODHWNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |