Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 10/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854741 | 0.76 | EP300 (0.40) | EP300PRMT5WDR77HDAC4DHODH | |
| SCHEMBL3118237 | 0.75 | CYP2A6 (0.50) | HRH3EP300PRMT5WDR77HDAC4 | |
| SCHEMBL13637169 | 0.75 | RAB9A (0.44) | PRMT5WDR77HDAC4DHODHWNT3A | |
| SCHEMBL13625507 | 0.74 | XDH (0.42) | EP300HDAC4DHODHWNT3A | |
| SCHEMBL6880455 | 0.73 | EP300 (0.44) | EP300HDAC4DHODHWNT3A | |
| SCHEMBL6880980 | 0.73 | AOC3 (0.47) | AOC3HRH3CHRNA7WNT3A | |
| SCHEMBL6880986 | 0.73 | AOC3 (0.47) | AOC3HRH3CHRNA7WNT3A | |
| SCHEMBL6878881 | 0.72 | EP300 (0.41) | EP300PRMT5WDR77HDAC4DHODH | |
| SCHEMBL6852546 | 0.72 | WNT3A (0.42) | EP300PRMT5WDR77HDAC4DHODH | |
| SCHEMBL6215593 | 0.72 | MKNK1 (0.50) | EP300PRMT5WDR77HDAC4DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | Q6ZSR9, ACSL6, RPS4Y1 | AOC3 1365/4885HRH3 4185/4885EP300 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.