Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886952 | 0.89 | ACHE (0.33) | — | |
| SCHEMBL6885470 | 0.81 | KDM4E (0.32) | — | |
| SCHEMBL6889023 | 0.77 | LMNA (0.36) | — | |
| SCHEMBL6886930 | 0.73 | KDM4E (0.38) | ALDH1A1 | |
| SCHEMBL6880481 | 0.71 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL6881900 | 0.71 | SLC29A1 (0.48) | — | |
| SCHEMBL6885467 | 0.66 | SLC5A1 (0.31) | — | |
| SCHEMBL6887345 | 0.65 | KDM4E (0.45) | — | |
| SCHEMBL6886954 | 0.64 | ACHE (0.56) | ALDH1A1 | |
| SCHEMBL6880948 | 0.64 | BCHE (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |