Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886954 | 0.89 | ACHE (0.56) | SLC29A1TAS1R3TAS1R1ADORA2AADORA2B | |
| SCHEMBL13471113 | 0.88 | SLC29A1 (0.59) | SLC29A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6885472 | 0.82 | SLC29A1 (0.52) | SLC29A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL13468263 | 0.79 | ADORA2A (0.58) | SLC29A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9681390 | 0.79 | HINT1 (0.51) | SLC29A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6889026 | 0.77 | LMNA (0.69) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL18479661 | 0.76 | SLC29A1 (0.61) | SLC29A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL27621467 | 0.75 | SLC29A1 (0.66) | SLC29A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6758859 | 0.75 | SLC29A1 (0.61) | SLC29A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6758863 | 0.75 | SLC29A1 (0.61) | SLC29A1ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |