Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942062 | 0.78 | HTR6 (0.50) | HTR6LMNADRD2CYP1A2CYP2D6 | |
| SCHEMBL7942059 | 0.78 | HTR6 (0.50) | HTR6LMNADRD2CYP1A2CYP2D6 | |
| SCHEMBL7325069 | 0.76 | LMNA (0.50) | HTR6LMNADRD2CYP1A2CYP2D6 | |
| SCHEMBL11796344 | 0.75 | HTR6 (0.43) | HTR6LMNADRD2CYP1A2CYP2D6 | |
| SCHEMBL11796340 | 0.75 | HTR6 (0.43) | HTR6LMNADRD2CYP1A2CYP2D6 | |
| SCHEMBL9204207 | 0.73 | LMNA (0.48) | HTR6LMNADRD2CYP1A2CYP2D6 | |
| SCHEMBL170602 | 0.72 | MEN1 (0.55) | HTR6LMNADRD2CYP1A2CYP2D6 | |
| Propene SCHEMBL28136016 | 0.66 | MAPT (0.39) | HTR6LMNADRD2CYP1A2CYP2D6 | |
| SCHEMBL23095418 | 0.66 | MAPT (0.48) | LMNACYP1A2CYP2D6ALOX15TP53 | |
| SCHEMBL24293002 | 0.65 | LMNA (0.40) | HTR6LMNADRD2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091050-A1 | OLIGOMER-TRICYCLIC CONJUGATES | NEKTAR THERAPEUTICS (US) | 2011-07-28 | — | — | WO | disclosed |