Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599045 | 0.78 | DRD2 (0.43) | LMNADRD2CYP1A2CYP2D6TSHR | |
| SCHEMBL7942059 | 0.78 | HTR6 (0.50) | LMNADRD2CYP1A2CYP2D6HTR1A | |
| SCHEMBL7942062 | 0.78 | HTR6 (0.50) | LMNADRD2CYP1A2CYP2D6HTR1A | |
| SCHEMBL6882019 | 0.76 | HTR6 (0.38) | LMNADRD2CYP1A2CYP2D6HTR1A | |
| SCHEMBL11796344 | 0.75 | HTR6 (0.43) | LMNADRD2CYP1A2CYP2D6HTR1A | |
| SCHEMBL11796340 | 0.75 | HTR6 (0.43) | LMNADRD2CYP1A2CYP2D6HTR1A | |
| SCHEMBL17425294 | 0.72 | LMNA (0.44) | LMNADRD2CYP1A2CYP2D6HTR1A | |
| SCHEMBL3769766 | 0.72 | MEN1 (0.55) | LMNADRD2CYP1A2CYP2D6HTR1A | |
| SCHEMBL170602 | 0.72 | MEN1 (0.55) | LMNADRD2CYP1A2CYP2D6HTR1A | |
| SCHEMBL15570432 | 0.71 | MEN1 (0.45) | LMNADRD2CYP1A2CYP2D6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346742-B2 | Compositions and methods for the treatment of fibromyalgia pain | CELLIX BIO PRIVATE LIMITED (IN) | 2016-05-24 | — | — | US | disclosed |
| US-20150111966-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF FIBROMYALGIA PAIN | CELLIX BIO PRIVATE LIMITED (IN) | 2015-04-23 | — | — | US | disclosed |
| EP-0581767-B1 | 5H-DIBENZO(a,d)CYCLOHEPTENES AS MUSCARINIC RECEPTOR ANTAGONISTS | MERRELL PHARMA INC (US) | 1997-09-03 | — | — | EP | disclosed |
| US-5508280-A | 5H-Dibenzo (A,D) cycloheptenes as muscarinic receptor antagonists | MERRELL PHARMACEUTICALS, INC. (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0581767-A1 | 5H-DIBENZO(a,d)CYCLOHEPTENES AS MUSCARINIC RECEPTOR ANTAGONISTS. | MERRELL DOW PHARMA (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1991017973-A1 | 5H-DIBENZO(a,d)CYCLOHEPTENES AS MUSCARINIC RECEPTOR ANTAGONISTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-11-28 | — | — | WO | disclosed |
| US-4048223-A | 3-Dimethylsulfamoyl-5-[amino(alkyl or alkylidene)]-5H-dibenzo [a,d]cycloheptenes | MERCK & CO., INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-3978121-A | 5H Dibenzo[a,d]cycloheptene derivatives | MERCK & CO., INC. (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111966-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF FIBROMYALGIA PAIN | SLC5A1, KYNU, HLA-DRB1 | LMNA 1411/4885DRD2 3091/4885CYP1A2 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.