Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1451327 | 0.82 | ALDH1A1 (0.62) | KMT2ACYP3A4CYP2C9ALDH1A1KDM4E | |
| SCHEMBL6883346 | 0.82 | KMT2A (0.63) | KMT2ACYP3A4CYP2C9ALDH1A1KDM4E | |
| SCHEMBL473766 | 0.81 | KMT2A (0.58) | KMT2ACYP3A4CYP2C9ALDH1A1KDM4E | |
| SCHEMBL31268624 | 0.81 | KMT2A (0.58) | KMT2ACYP3A4CYP2C9ALDH1A1KDM4E | |
| SCHEMBL9629674 | 0.76 | ALDH1A1 (0.71) | KMT2ACYP3A4CYP2C9ALDH1A1KDM4E | |
| SCHEMBL6883647 | 0.76 | KMT2A (0.49) | KMT2ACYP3A4CYP2C9ALDH1A1KDM4E | |
| SCHEMBL6873425 | 0.75 | KMT2A (0.51) | KMT2ACYP3A4CYP2C9ALDH1A1KDM4E | |
| SCHEMBL18928220 | 0.74 | KMT2A (0.65) | KMT2ACYP3A4CYP2C9ALDH1A1KDM4E | |
| SCHEMBL6880258 | 0.74 | KMT2A (0.52) | KMT2ACYP3A4CYP2C9ALDH1A1KDM4E | |
| Phthalic Acid SCHEMBL6320551 | 0.73 | ALDH1A1 (0.56) | KMT2AALDH1A1KDM4EGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242891-A1 | Production of keto acids | CAMPBELL JONATHAN (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1442009-A1 | PRODUCTION OF KETO ACIDS | Ciba SC Holding AG (CH) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037846-A1 | PRODUCTION OF KETO ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242891-A1 | Production of keto acids | PKLR, KHK, ME1 | KMT2A 552/4885CYP3A4 625/4885CYP2C9 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.