Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 2/20 | 0.41 |
| ▸ | ATP4B | P51164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882972 | 1.00 | NFE2L2 (0.54) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL7187276 | 0.83 | TRPA1 (0.55) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL44502 | 0.80 | NFE2L2 (0.68) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL6360540 | 0.80 | NFE2L2 (0.68) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL5411617 | 0.80 | NFE2L2 (0.68) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL44503 | 0.80 | NFE2L2 (0.68) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL9540538 | 0.80 | NFE2L2 (0.68) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| (Z)-1,2-Diphenylethene SCHEMBL7653143 | 0.80 | NFE2L2 (0.68) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| (Z)-1,2-Diphenylethene SCHEMBL7653150 | 0.80 | NFE2L2 (0.68) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL7187435 | 0.79 | TRPA1 (0.52) | NFE2L2TRPA1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055278-A1 | Soluble tetrahedral compounds for use in electroluminescent devices | NATIONAL SCIENCE FOUNDATION | 2003-03-20 | — | — | US | claimed |
| WO-2001083410-A1 | SOLUBLE TETRAHEDRAL COMPOUNDS FOR USE IN ELECTROLUMINESCENT DEVICES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-11-08 | — | — | WO | claimed |
| US-6824890-B2 | TOPOLOGICAL STRATEGY FOR DESIGNING AMORPHOUS MOLECULAR SOLIDS FOR FORMING THIN FILMS IN OPTOELECTRONIC DEVICES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-11-30 | — | — | US | disclosed |
| US-20030055278-A1 | Soluble tetrahedral compounds for use in electroluminescent devices | NATIONAL SCIENCE FOUNDATION | 2003-03-20 | — | — | US | disclosed |
| WO-2001083410-A1 | SOLUBLE TETRAHEDRAL COMPOUNDS FOR USE IN ELECTROLUMINESCENT DEVICES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055278-A1 | Soluble tetrahedral compounds for use in electroluminescent devices | PAX3, EPCAM, PAXBP1 | NFE2L2 2377/4885TRPA1 463/4885MEN1 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.