Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 2/20 | 0.41 |
| ▸ | ATP4B | P51164 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187276 | 0.84 | TRPA1 (0.55) | TRPA1NFE2L2MEN1KMT2AKDM4E | |
| SCHEMBL25878850 | 0.84 | NFE2L2 (0.50) | TRPA1NFE2L2MEN1KMT2AATP4A | |
| SCHEMBL6882972 | 0.79 | NFE2L2 (0.54) | TRPA1NFE2L2MEN1KMT2AATP4A | |
| SCHEMBL6882976 | 0.79 | NFE2L2 (0.54) | TRPA1NFE2L2MEN1KMT2AATP4A | |
| SCHEMBL7188756 | 0.78 | NFE2L2 (0.53) | TRPA1NFE2L2MEN1KMT2AATP4A | |
| SCHEMBL6433934 | 0.76 | NFE2L2 (0.55) | TRPA1NFE2L2MEN1KMT2AATP4A | |
| SCHEMBL20482327 | 0.76 | NFE2L2 (0.55) | TRPA1NFE2L2MEN1KMT2AATP4A | |
| SCHEMBL17836940 | 0.74 | NFE2L2 (0.44) | TRPA1NFE2L2MEN1KMT2AATP4A | |
| SCHEMBL44503 | 0.73 | NFE2L2 (0.68) | TRPA1NFE2L2MEN1KMT2ACHAT | |
| SCHEMBL44502 | 0.73 | NFE2L2 (0.68) | TRPA1NFE2L2MEN1KMT2ACHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276807-A1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | Dow Corning Corporation (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001083608-A1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | DOW CORNING CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |