Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.42 |
| ▸ | CTSA | P10619 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687472 | 0.90 | KMT2A (0.41) | CTSAALDH1A1MAPT | |
| SCHEMBL687304 | 0.90 | KEAP1 (0.41) | CTSAALDH1A1MAPT | |
| SCHEMBL687932 | 0.87 | EGLN1 (0.44) | PTGER4PTGDRCTSAALDH1A1P2RY14 | |
| SCHEMBL688046 | 0.87 | CTSA (0.42) | CTSAALDH1A1P2RX7 | |
| SCHEMBL688008 | 0.86 | CTSA (0.41) | CTSAALDH1A1 | |
| SCHEMBL688232 | 0.86 | CTSA (0.42) | CTSA | |
| SCHEMBL688146 | 0.85 | CTSA (0.41) | CTSAALDH1A1 | |
| SCHEMBL686896 | 0.84 | PTGER3 (0.44) | CTSAP2RY14 | |
| SCHEMBL29371834 | 0.84 | PTGER3 (0.44) | CTSAP2RY14 | |
| SCHEMBL688495 | 0.84 | POLB (0.39) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |