SCHEMBL6883471

SCHEMBL6883471

O=C(Oc1c(-c2ccccc2)cccc1-c1ccccc1C(=O)O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.50
SLC6A3 Q01959 1/20 0.45
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
FABP3 P05413 1/20 0.43
FABP4 P15090 1/20 0.43
FABP5 Q01469 1/20 0.43
HTT P42858 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MYC P01106 1/20 0.41
TOP1 P11387 1/20 0.41
BCAT2 O15382 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6264269 0.91 HNF4A (0.53) HNF4ASLC6A3ESR1ESR2FABP3
SCHEMBL8778066 0.82 HNF4A (0.51) HNF4ASLC6A3ESR1ESR2FABP3
SCHEMBL30186936 0.81 PARP10 (0.50) HNF4ASLC6A3ESR1ESR2FABP3
SCHEMBL17554290 0.81 PARP10 (0.50) HNF4ASLC6A3ESR1ESR2FABP3
SCHEMBL2484009 0.80 TOP1 (0.55) SLC6A3ESR1ESR2HTTMAPT
SCHEMBL6870291 0.78 PARP10 (0.54) SLC6A3ESR1ESR2MAPTKMT2A
SCHEMBL6864415 0.78 MAOA (0.51) HNF4ASLC6A3ESR1ESR2MAPT
SCHEMBL6870248 0.78 SLC6A3 (0.63) SLC6A3ESR1ESR2MAPTKMT2A
SCHEMBL7407371 0.76 HNF4A (0.73) HNF4AFABP3FABP4FABP5MAPT
SCHEMBL18143536 0.76 HNF4A (0.58) HNF4AESR1FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6720287-B2 WHEN AN AROMATIC DICARBOXYLATE IS ENCAPSULATEDTOGETHER WITH THE DIAZONIUM SALT COMPOUND, GENERATION OF PHOTODECOMPOSITION STAIN IS REDUCED AND SHELF LIFE IS IMPROVED FUJI PHOTO FILM CO., LTD. (JP) 2004-04-13 US disclosed
US-20030045426-A1 Heat sensitive recording material and microcapsule solution FUJI PHOTO FILM CO., LTD. 2003-03-06 US disclosed