SCHEMBL8778066

SCHEMBL8778066

O=C(Oc1c(C(=O)O)cccc1-c1ccccc1)c1ccc(O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.51
SENP1 Q9P0U3 1/20 0.49
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
LMNA P02545 2/20 0.46
ALDH1A1 P00352 2/20 0.46
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
MMP9 P14780 1/20 0.41
CDC25B P30305 1/20 0.41
ATM Q13315 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPT P10636 1/20 0.40
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
SLC6A3 Q01959 1/20 0.40
EGFR P00533 1/20 0.40
RXRA P19793 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6264269 0.91 HNF4A (0.53) HNF4AESR1ESR2LMNAALDH1A1
SCHEMBL8778012 0.86 SLC6A2 (0.49) SENP1ESR1ESR2FABP3FABP4
SCHEMBL9571703 0.85 SENP1 (0.51) SENP1ESR1ESR2LMNAALDH1A1
SCHEMBL8778030 0.84 NR4A1 (0.46) SENP1ESR1ESR2ALDH1A1FABP3
SCHEMBL6883471 0.82 HNF4A (0.50) HNF4AESR1ESR2LMNAALDH1A1
SCHEMBL18143536 0.80 HNF4A (0.58) HNF4AESR1LMNAALDH1A1FABP3
SCHEMBL8766835 0.79 ALDH1A1 (0.62) SENP1ESR1ESR2LMNAALDH1A1
SCHEMBL27898043 0.77 RXRA (0.55) SENP1ESR1ESR2LMNAALDH1A1
SCHEMBL1358288 0.77 KDM4E (0.63) HNF4AESR1LMNAALDH1A1FABP3
SCHEMBL8778061 0.77 ESR1 (0.55) HNF4ASENP1ESR1ESR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585127-B1 Thermal Recording sheet JUJO PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5405821-A Containing a 4-hydroxyphenylarylsulfone color developer NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-04-11 US disclosed