Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 2/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.64 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.61 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.61 |
| ▸ | P2RY1 | P47900 | 7/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.60 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.60 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.60 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.60 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.59 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19442379 | 0.84 | P2RY1 (0.72) | GPR17P2RX3P2RX2P2RY1P2RX4 | |
| SCHEMBL14853693 | 0.84 | P2RY1 (0.72) | GPR17P2RX3P2RX2P2RY1P2RX4 | |
| SCHEMBL20901220 | 0.84 | P2RY1 (0.72) | GPR17P2RX3P2RX2P2RY1P2RX4 | |
| SCHEMBL14948858 | 0.84 | P2RY1 (0.72) | GPR17P2RX3P2RX2P2RY1P2RX4 | |
| SCHEMBL14928757 | 0.84 | P2RY1 (0.72) | GPR17P2RX3P2RX2P2RY1P2RX4 | |
| SCHEMBL625113 | 0.84 | P2RY1 (0.72) | GPR17P2RX3P2RX2P2RY1P2RX4 | |
| SCHEMBL309060 | 0.83 | P2RY1 (0.71) | P2RX3P2RX2P2RY1P2RX4ENPP1 | |
| SCHEMBL6882745 | 0.83 | ADORA3 (0.62) | — | |
| SCHEMBL1533270 | 0.83 | ADORA3 (0.62) | — | |
| SCHEMBL14178291 | 0.81 | IMPDH2 (0.77) | GPR17NT5EP2RX3P2RX2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040241706-A1 | Highly specific modulators of GTPases for target validation | IRM, LLC | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040241706-A1 | Highly specific modulators of GTPases for target validation | CDC42, ARHGDIB, ARHGEF2 | GPR17 3824/4885NT5E 2436/4885P2RX3 3919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.