Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875960 | 0.93 | RNASEH1 (0.44) | RNASEH1PIN1LMNAMAPTKDM4E | |
| SCHEMBL6884865 | 0.92 | ALDH1A1 (0.39) | PIN1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL6877025 | 0.85 | PIN1 (0.53) | RNASEH1PIN1ERCC1FEN1ERCC4 | |
| SCHEMBL6884737 | 0.84 | UBE2I (0.43) | PIN1LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL6883616 | 0.83 | PIN1 (0.40) | RNASEH1PIN1ALDH1A1ERCC1FEN1 | |
| SCHEMBL6882673 | 0.82 | ERCC1 (0.42) | RNASEH1PIN1KDM4EALDH1A1HPGD | |
| SCHEMBL6883326 | 0.82 | ALDH1A1 (0.44) | RNASEH1PIN1LMNAMAPTKDM4E | |
| SCHEMBL6883865 | 0.82 | PIN1 (0.40) | RNASEH1PIN1ERCC1FEN1ERCC4 | |
| SCHEMBL6885416 | 0.81 | HSP90AA1 (0.41) | RNASEH1PIN1ERCC1FEN1ERCC4 | |
| SCHEMBL6883344 | 0.81 | PIN1 (0.43) | RNASEH1PIN1KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | disclosed |