SCHEMBL6883783

SCHEMBL6883783

C=CCOc1cccc(-c2[c]cccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.40
ADORA1 P30542 1/20 0.38
GAA P10253 2/20 0.38
BCHE P06276 1/20 0.38
ALDH1A1 P00352 1/20 0.37
FGFR1 P11362 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
KAT6A Q92794 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28231902 0.83 CA12 (0.41) SIRT1ALDH1A1FGFR1MEN1LMNA
SCHEMBL22085949 0.81 MEN1 (0.46) SIRT1ADORA1GAABCHEFGFR1
SCHEMBL6963144 0.80 MAPT (0.47) GAAALDH1A1FGFR1LMNAMAPT
SCHEMBL4218764 0.80 CYP1A2 (0.35) GAAMAPTKDM4E
SCHEMBL4981424 0.79 LTA4H (0.47) SIRT1ADORA1GAABCHEALDH1A1
SCHEMBL3729005 0.78 KDM4E (0.47) GAAALDH1A1MEN1LMNAMAPT
SCHEMBL8074390 0.78 MAOB (0.51) BCHE
SCHEMBL6883786 0.77 SIRT1 (0.40) SIRT1ADORA1GAABCHEALDH1A1
SCHEMBL1520719 0.75 MEN1 (0.50) GAABCHEALDH1A1FGFR1MEN1
SCHEMBL15377757 0.74 MAPT (0.45) SIRT1BCHEALDH1A1FGFR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040033317-A1 Surface-active photoinitators CIBA SPECIALTY CHEMICALS CORP. 2004-02-19 US disclosed