Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22085949 | 0.88 | MEN1 (0.46) | SIRT1MEN1LMNAMAPTKMT2A | |
| SCHEMBL4981424 | 0.86 | LTA4H (0.47) | SIRT1KDM4ENPC1RAB9AADORA1 | |
| SCHEMBL15377757 | 0.85 | MAPT (0.45) | SIRT1MEN1LMNAMAPTKMT2A | |
| SCHEMBL19856490 | 0.81 | CA12 (0.47) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9469380 | 0.80 | SLC6A2 (0.47) | SIRT1LMNAADRA2AADRA2BADRA2C | |
| SCHEMBL1520719 | 0.78 | MEN1 (0.50) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9469826 | 0.78 | GABRG2 (0.46) | ADRA2AADRA2BADRA2C | |
| SCHEMBL534325 | 0.78 | RXRA (0.58) | MAPTSMN1; SMN2KDM4ERAB9AGAA | |
| SCHEMBL6883783 | 0.77 | SIRT1 (0.40) | SIRT1MEN1LMNAMAPTKMT2A | |
| SCHEMBL482465 | 0.77 | CA12 (0.48) | MEN1LMNAMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570482-B | A kind of 1,3-bis-replaces the preparation method of allenic compound | 北京大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-103570482-A | Preparation method of 1,3-disubstituted allene compound | UNIV BEIJING | 2014-02-12 | — | — | CN | disclosed |
| US-20040033317-A1 | Surface-active photoinitators | CIBA SPECIALTY CHEMICALS CORP. | 2004-02-19 | — | — | US | disclosed |