SCHEMBL6884008

SCHEMBL6884008

CCCCCCCCOc1cc(C#Cc2ccccc2)c(OCCCCCCCC)cc1C#Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.46
ALDH1A1 P00352 2/20 0.45
HPGD P15428 1/20 0.45
TLR8 Q9NR97 2/20 0.43
NR1I2 O75469 2/20 0.43
CHRM2 P08172 2/20 0.43
ADRA2A P08913 2/20 0.43
OPRK1 P41145 2/20 0.43
HTR2B P41595 2/20 0.43
SLC6A3 Q01959 2/20 0.43
LMNA P02545 2/20 0.43
MEN1 O00255 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
TSHR P16473 2/20 0.43
NOS1 P29475 1/20 0.43
PTPN11 Q06124 2/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12431348 1.00 LTA4H (0.46) LTA4HALDH1A1HPGDTLR8NR1I2
SCHEMBL13965652 0.94 TSHR (0.42) LTA4HALDH1A1HPGDTLR8NR1I2
SCHEMBL13965659 0.91 LTA4H (0.39) LTA4HALDH1A1HPGDTLR8NR1I2
SCHEMBL18470977 0.86 ALDH1A1 (0.36) LTA4HALDH1A1HPGDTLR8NR1I2
SCHEMBL24819416 0.85 ALDH1A1 (0.40) ALDH1A1HPGDTLR8NR1I2CHRM2
SCHEMBL13965700 0.84 TSHR (0.35) LTA4HALDH1A1HPGDTLR8NR1I2
SCHEMBL14366092 0.83 MMP2 (0.49) ALDH1A1HPGDNR1I2CHRM2ADRA2A
SCHEMBL13965679 0.83 THRA (0.42) ALDH1A1HPGDNR1I2CHRM2ADRA2A
SCHEMBL13965638 0.83 THRA (0.42) ALDH1A1HPGDNR1I2CHRM2ADRA2A
SCHEMBL14366139 0.83 MMP2 (0.49) ALDH1A1HPGDNR1I2CHRM2ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051646-B1 EFFICIENT PHOTOLUMINESCENT POLARIZERS, PROCESS FOR FORMING, AND APPLICATION IN DISPLAY DEVICES LANDQART (CH) 2004-03-03 EP disclosed
US-6594062-B1 Efficient photoluminescent polarizers, process for forming, and application in display devices LANDQART (CH) 2003-07-15 US disclosed
EP-1051646-A1 EFFICIENT PHOTOLUMINESCENT POLARIZERS, PROCESS FOR FORMING, AND APPLICATION IN DISPLAY DEVICES Landqart (CH) 2000-11-15 EP disclosed
WO-1999039222-A1 EFFICIENT PHOTOLUMINESCENT POLARIZERS, PROCESS FOR FORMING, AND APPLICATION IN DISPLAY DEVICES LANDQART (CH) 1999-08-05 WO disclosed