Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 11/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.44 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6884013 | 0.86 | CHRNA7 (0.44) | CHRNA7CHRNA10CHRNA9RELAMAPT | |
| SCHEMBL6876942 | 0.81 | TRPA1 (0.42) | CHRNA7CHRNA10CHRNA9RELAMAPT | |
| SCHEMBL6876940 | 0.81 | TRPA1 (0.42) | CHRNA7CHRNA10CHRNA9RELAMAPT | |
| SCHEMBL13309559 | 0.80 | CHRNA7 (0.48) | CHRNA7CHRNA10CHRNA9RELAMAPT | |
| Propene SCHEMBL28139918 | 0.80 | NFE2L2 (0.38) | CHRNA7CHRNA10CHRNA9RELAMAPT | |
| SCHEMBL28320973 | 0.78 | NFE2L2 (0.41) | CHRNA7CHRNA10CHRNA9RELAMAPT | |
| Styrene SCHEMBL28131526 | 0.78 | ALDH1A1 (0.50) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| Dodecane SCHEMBL27503014 | 0.77 | ALDH1A1 (0.64) | TP53MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| Hexadecane SCHEMBL27958494 | 0.77 | ALDH1A1 (0.64) | TP53MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| Styrene SCHEMBL1074288 | 0.77 | ALDH1A1 (0.64) | TP53MEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824890-B2 | TOPOLOGICAL STRATEGY FOR DESIGNING AMORPHOUS MOLECULAR SOLIDS FOR FORMING THIN FILMS IN OPTOELECTRONIC DEVICES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-11-30 | — | — | US | disclosed |
| US-20030055278-A1 | Soluble tetrahedral compounds for use in electroluminescent devices | NATIONAL SCIENCE FOUNDATION | 2003-03-20 | — | — | US | disclosed |
| WO-2001083410-A1 | SOLUBLE TETRAHEDRAL COMPOUNDS FOR USE IN ELECTROLUMINESCENT DEVICES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055278-A1 | Soluble tetrahedral compounds for use in electroluminescent devices | PAX3, EPCAM, PAXBP1 | CHRNA7 1310/4885CHRNA10 995/4885CHRNA9 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.