Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.63 |
| ▸ | IGF1R | P08069 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154950 | 0.84 | KLF10 (0.45) | ALOX15IGF1RBACE1HIF1ACYP1A2 | |
| SCHEMBL6155280 | 0.83 | KLF10 (0.44) | ALOX15IGF1RBACE1ADRB2 | |
| SCHEMBL27557366 | 0.83 | BCHE (0.47) | ALOX15IGF1R | |
| SCHEMBL6155799 | 0.81 | LTA4H (0.55) | ALOX15IGF1RKDM4EALDH1A1TP53 | |
| SCHEMBL6155726 | 0.80 | LTA4H (0.53) | KDM4EALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL2307446 | 0.80 | ALOX15 (1.00) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL31556198 | 0.78 | ALOX15 (0.95) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL31556189 | 0.78 | ALOX15 (0.95) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL10335381 | 0.78 | ALOX15 (0.95) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL31556196 | 0.78 | ALOX15 (0.95) | ALOX15IGF1RMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |