Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878304 | 0.91 | PTGES (0.42) | ERCC1FEN1ERCC4ADORA1PTGES | |
| SCHEMBL6018618 | 0.90 | PTGES (0.40) | ERCC1FEN1ERCC4PTGES | |
| SCHEMBL6651068 | 0.78 | ERCC1 (0.52) | ERCC1FEN1ERCC4EGLN1SMN1; SMN2 | |
| SCHEMBL6884591 | 0.76 | ERCC1 (0.50) | ERCC1FEN1ERCC4EGLN1TDP1 | |
| SCHEMBL6649380 | 0.76 | ERCC1 (0.54) | ERCC1FEN1ERCC4EGLN1SMN1; SMN2 | |
| SCHEMBL6883227 | 0.75 | ERCC1 (0.47) | ERCC1FEN1ERCC4EGLN1SMN1; SMN2 | |
| SCHEMBL6883233 | 0.73 | ATM (0.39) | ERCC1FEN1ERCC4ALDH1A1 | |
| SCHEMBL6017883 | 0.73 | KCNE1 (0.52) | ERCC1FEN1ERCC4TDP1SMN1; SMN2 | |
| SCHEMBL7156067 | 0.73 | ERCC1 (0.47) | ERCC1FEN1ERCC4EGLN1SMN1; SMN2 | |
| SCHEMBL6883711 | 0.73 | NAMPT (0.35) | ERCC1FEN1ERCC4SMN1; SMN2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | disclosed |