Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885094 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11HDAC1HDAC6PDE3B | |
| SCHEMBL6885245 | 0.84 | HMGCR (0.47) | CYP4F2CYP4A11HDAC4MEF2DHMGCR | |
| SCHEMBL6156152 | 0.84 | HMGCR (0.47) | CYP4F2CYP4A11HDAC4MEF2DHMGCR | |
| SCHEMBL6878729 | 0.74 | FFAR1 (0.37) | HDAC1HDAC6PDE3BPDE3AP2RY12 | |
| SCHEMBL4841588 | 0.73 | CYSLTR2 (0.42) | HDAC1HDAC6PDE3BPDE3AP2RY12 | |
| SCHEMBL6885100 | 0.73 | CYP4F2 (0.44) | CYP4F2CYP4A11HDAC1HDAC6PDE3B | |
| SCHEMBL6878841 | 0.73 | HDAC1 (0.40) | HDAC1HDAC6 | |
| SCHEMBL6881439 | 0.72 | HMGCR (0.35) | HMGCR | |
| SCHEMBL8891543 | 0.70 | APP (0.50) | ALOX5APP | |
| SCHEMBL6885253 | 0.70 | CYP4F2 (0.45) | CYP4F2CYP4A11HDAC1HDAC6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |