Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 18/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878729 | 0.91 | FFAR1 (0.37) | FFAR1 | |
| SCHEMBL6885404 | 0.80 | CYSLTR2 (0.48) | FFAR1FFAR4 | |
| SCHEMBL6878841 | 0.71 | HDAC1 (0.40) | FFAR1 | |
| SCHEMBL7775456 | 0.71 | FFAR1 (0.44) | FFAR1MAPTRXFP1FFAR4 | |
| SCHEMBL6885569 | 0.70 | FFAR1 (0.46) | FFAR1MAPTRXFP1FFAR4 | |
| SCHEMBL24339424 | 0.69 | FFAR1 (0.56) | FFAR1MAPTRXFP1FFAR4 | |
| SCHEMBL7985128 | 0.68 | ACE2 (0.34) | — | |
| SCHEMBL5871915 | 0.67 | KDM4E (0.35) | MAPT | |
| SCHEMBL1197247 | 0.67 | MAPT (0.78) | MAPTRXFP1 | |
| SCHEMBL6885053 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |