Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PDE6D | O43924 | 2/20 | 0.37 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | PDE6A | P16499 | 2/20 | 0.37 |
| ▸ | PDE6G | P18545 | 2/20 | 0.37 |
| ▸ | PDE6B | P35913 | 2/20 | 0.37 |
| ▸ | PDE6C | P51160 | 2/20 | 0.37 |
| ▸ | PDE6H | Q13956 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1925547 | 0.89 | MEN1 (0.41) | KDM4ESMN1; SMN2AURKAAURKBHSD17B10 | |
| SCHEMBL6886953 | 0.85 | ADORA3 (0.34) | KDM4EMAPK1AURKAAURKBMEN1 | |
| SCHEMBL6887483 | 0.81 | CA2 (0.36) | AURKAAURKBMAPT | |
| SCHEMBL6267740 | 0.81 | AAK1 (0.34) | AURKAAURKBMEN1MAPTKMT2A | |
| SCHEMBL6886653 | 0.79 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2ALDH1A1MEN1LMNA | |
| SCHEMBL6888425 | 0.77 | MEN1 (0.39) | KDM4ESMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| SCHEMBL1927369 | 0.76 | KDM4E (0.45) | KDM4ESMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL1924625 | 0.76 | KDM4E (0.43) | KDM4ESMN1; SMN2AURKAAURKBHSD17B10 | |
| SCHEMBL22632825 | 0.75 | SMN1; SMN2 (0.62) | KDM4ESMN1; SMN2ALDH1A1MEN1LMNA | |
| SCHEMBL1925804 | 0.74 | DHODH (0.44) | KDM4EHSD17B10MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1431293-A1 | WATER-SOLUBLE PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2004-06-23 | — | — | EP | disclosed |