Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887483 | 0.91 | CA2 (0.36) | AAK1MAPTGRIN2BAURKAAURKB | |
| SCHEMBL6886653 | 0.86 | ALDH1A1 (0.42) | AAK1MAPTMEN1KMT2APTGS2 | |
| SCHEMBL1925547 | 0.85 | MEN1 (0.41) | MAPTAURKAAURKBMEN1TP53 | |
| SCHEMBL6886068 | 0.81 | KDM4E (0.41) | MAPTAURKAAURKBMEN1KMT2A | |
| SCHEMBL1924722 | 0.80 | KMO (0.45) | KMOMAPTGRIN2BMEN1KMT2A | |
| SCHEMBL1925215 | 0.80 | KMO (0.38) | KMOMAPTGRIN2BAURKAAURKB | |
| SCHEMBL6886953 | 0.80 | ADORA3 (0.34) | AURKAAURKBMEN1KMT2APTGS2 | |
| SCHEMBL1925457 | 0.78 | GRIN2B (0.37) | KMOMAPTGRIN2BMEN1TP53 | |
| Hydrochloric Acid SCHEMBL1925805 | 0.77 | GRIN2B (0.36) | KMOMAPTGRIN2BMEN1TP53 | |
| SCHEMBL1926062 | 0.76 | POLB (0.44) | KMOMAPTGRIN2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1604984-A1 | WATER-SOLUBLE PHENYLPYRIDAZINE DERIVATIVE AND MEDICINE CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1431293-A1 | WATER-SOLUBLE PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2004-06-23 | — | — | EP | disclosed |