Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HK1 | P19367 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL274281 | 0.83 | ALDH1A1 (0.46) | KDM4EHSD17B10ALDH1A1SMN1; SMN2NPC1 | |
| Bicarbonate SCHEMBL9678990 | 0.64 | GPR3 (0.76) | KDM4EEGFRHSD17B10ALDH1A1MAPT | |
| SCHEMBL7487890 | 0.63 | ALDH1A1 (0.70) | KDM4EEGFRHSD17B10CYP2C19ALDH1A1 | |
| SCHEMBL7971242 | 0.63 | MAPT (0.54) | KDM4EEGFRHSD17B10CYP2C19ALDH1A1 | |
| SCHEMBL24010348 | 0.60 | ALKBH5 (0.56) | KDM4EEGFRHSD17B10ALDH1A1LMNA | |
| SCHEMBL20595409 | 0.60 | KDM4E (0.53) | KDM4EEGFRHSD17B10ALDH1A1MAPT | |
| SCHEMBL26031841 | 0.60 | HSD17B10 (0.68) | KDM4EEGFRHSD17B10CYP2C19ALDH1A1 | |
| SCHEMBL984736 | 0.59 | EGFR (0.65) | KDM4EEGFRHSD17B10CYP2C19ALDH1A1 | |
| SCHEMBL30443220 | 0.59 | EGFR (0.65) | KDM4EEGFRHSD17B10CYP2C19ALDH1A1 | |
| SCHEMBL5001736 | 0.59 | ALDH1A1 (0.54) | KDM4EEGFRHSD17B10CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532153-B1 | AZEPINOINDOLE AND PYRIDOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X CEPTOR THERAPEUTICS INC (US) | 2012-02-29 | — | — | EP | disclosed |