Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HK1 | P19367 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988728 | 0.77 | KDM4E (0.42) | ALOX15MAPK1ALDH1A1KDM4EEGFR | |
| SCHEMBL8792194 | 0.73 | ALDH1A1 (0.62) | MAPTALOX15MAPK1MAOAALDH1A1 | |
| SCHEMBL6071546 | 0.72 | MAPT (0.48) | MAPTALOX15MAPK1MAOAALDH1A1 | |
| SCHEMBL8792311 | 0.70 | ALOX15 (1.00) | MAPTALOX15MAPK1MAOAALDH1A1 | |
| SCHEMBL8792316 | 0.70 | ALOX15 (1.00) | MAPTALOX15MAPK1MAOAALDH1A1 | |
| SCHEMBL30223561 | 0.68 | KDM4E (0.66) | MAPTALOX15MAPK1MAOAALDH1A1 | |
| SCHEMBL21524303 | 0.68 | MAOA (0.58) | MAPTALOX15MAPK1MAOAALDH1A1 | |
| SCHEMBL22118133 | 0.68 | KDM4E (0.66) | MAPTALOX15MAPK1MAOAALDH1A1 | |
| SCHEMBL17895740 | 0.68 | KDM4E (0.61) | MAPTALOX15MAPK1MAOAALDH1A1 | |
| Bicarbonate SCHEMBL9678990 | 0.66 | GPR3 (0.76) | MAPTALDH1A1TSHRKDM4EEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300340-B1 | USEFUL FOR THERAPY OF CANCER AND SOLID TUMORS | ADIR ET COMPAGNIE (FR) | 2001-10-09 | — | — | US | disclosed |
| US-6162822-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 2000-12-19 | — | — | US | disclosed |
| US-5854273-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 1998-12-29 | — | — | US | disclosed |