SCHEMBL688666

SCHEMBL688666

C=CCNc1ccc(N)cc1[N+](=O)[O-]

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 2/20 0.64
L3MBTL1 Q9Y468 3/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 5/20 0.49
TDP1 Q9NUW8 3/20 0.49
CYP3A4 P08684 2/20 0.49
ALOX15 P16050 2/20 0.49
TSHR P16473 3/20 0.46
MAPK1 P28482 2/20 0.46
RECQL P46063 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KAT2B Q92831 3/20 0.43
PRSS1 P07477 3/20 0.42
NPSR1 Q6W5P4 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 1/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358760 1.00 HCAR3 (0.64) HCAR3L3MBTL1MAPTMEN1KMT2A
SCHEMBL15018615 0.86 ALDH1A1 (0.50) HCAR3L3MBTL1MAPTMEN1KMT2A
SCHEMBL1252601 0.83 HCAR3 (0.66) HCAR3L3MBTL1MAPTMEN1KMT2A
SCHEMBL7099894 0.83 ALDH1A1 (0.53) HCAR3L3MBTL1MAPTMEN1KMT2A
SCHEMBL1934590 0.82 HCAR3 (0.64) HCAR3L3MBTL1MAPTMEN1KMT2A
SCHEMBL3220892 0.82 HCAR3 (0.64) HCAR3L3MBTL1MAPTMEN1KMT2A
SCHEMBL2336839 0.80 HCAR3 (0.61) HCAR3L3MBTL1MAPTMEN1KMT2A
SCHEMBL7130826 0.78 HCAR3 (0.60) HCAR3MAPTMEN1KMT2AALDH1A1
SCHEMBL8893097 0.78 HCAR3 (1.00) HCAR3MAPT
SCHEMBL15822762 0.78 KAT2B (0.61) HCAR3L3MBTL1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 714 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US claimed
EP-3873407-B1 TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING HENKEL AG & CO KGAA (DE) 2025-04-09 EP claimed
EP-4247323-B1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2024-09-04 EP claimed
US-20230414484-A1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2023-12-28 US claimed
CN-117222397-A Granular hair dyeing composition 威娜德国有限责任公司 2023-12-12 CN claimed
EP-3873407-A1 TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING Henkel AG & Co. KGaA (DE) 2021-09-08 EP claimed
US-5685881-A Aromatic allylaminonitro compounds, hair dye compositions containing aromatic allylaminonitio compounds, and synthetic and natural fiber dyeing process HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1997-11-11 US claimed
EP-0671900-B1 ALLYLAMINO-NITROAROMATES HENKEL KGAA (DE) 1996-08-14 EP claimed
EP-0671900-A1 ALLYLAMINO-NITROAROMATES. HENKEL KGAA (DE) 1995-09-20 EP claimed
WO-1994012149-A1 ALLYLAMINO-NITROAROMATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-06-09 WO claimed
EP-4710913-A2 METHOD AND APPARATUS FOR DYEING HAIR FIBRES USING RADIO FREQUENCY ELECTROMAGNETIC RADIATION Jemella Limited (GB) 2026-03-18 EP disclosed
EP-3727307-B1 METHOD AND APPARATUS FOR DYEING HAIR FIBRES USING RADIO FREQUENCY ELECTROMAGNETIC RADIATION JEMELLA LTD (GB) 2026-01-28 EP disclosed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US disclosed
EP-3941424-B1 HAIR COLORANT COMPOSITIONS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2025-07-16 EP disclosed
EP-3873407-B1 TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING HENKEL AG & CO KGAA (DE) 2025-04-09 EP disclosed
EP-0671900-B1 ALLYLAMINO-NITROAROMATES HENKEL KGAA (DE) 1996-08-14 EP disclosed
EP-0671900-A1 ALLYLAMINO-NITROAROMATES. HENKEL KGAA (DE) 1995-09-20 EP disclosed
WO-1994012149-A1 ALLYLAMINO-NITROAROMATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-06-09 WO disclosed
US-5041143-A N,N'-disubstituted nitro-para-phenylenediamines, and dyeing compositions containing the same L'OREAL (FR) 1991-08-20 US disclosed
US-4910341-A Reacting chloroethyl chloroformate with 4-halo-3-nitroaniline in presence of a base; cyclization; alkaline hydrolysis L'OREAL (FR) 1990-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230414484-A1 GRANULATED HAIR DYE COMPOSITION SHH, CUTA, DSG1 HCAR3 2509/4885L3MBTL1 4618/4885MAPT 654/4885
US-12364660-B2 Granulated hair dye composition SHH, CUTA, DSG1 HCAR3 2509/4885L3MBTL1 4618/4885MAPT 654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.