Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779587 | 0.86 | DRD2 (0.42) | MEN1KMT2APOLBDRD2DRD4 | |
| SCHEMBL6886685 | 0.82 | DRD2 (0.47) | DRD2DRD4 | |
| Oxalic Acid SCHEMBL5782031 | 0.76 | MEN1 (0.41) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL5815276 | 0.75 | KCNH2 (0.48) | DRD2DRD4 | |
| SCHEMBL5780528 | 0.74 | KCNH2 (0.45) | — | |
| SCHEMBL5781339 | 0.74 | MAOA (0.48) | HTR1ASLC6A4ATM | |
| SCHEMBL5778111 | 0.71 | KCNH2 (0.50) | DRD2DRD4 | |
| Oxalic Acid SCHEMBL5782849 | 0.70 | KDM4E (0.41) | MEN1KMT2AALDH1A1SIGMAR1MAPT | |
| SCHEMBL5783805 | 0.70 | MAOA (0.40) | MCHR1MEN1KMT2AALDH1A1ATM | |
| SCHEMBL5803181 | 0.70 | DCPS (0.46) | MEN1KMT2ADRD2DRD4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784192-B2 | NA+ CHANNEL INHIBITORY ACTION IS USEFUL FOR THERAPY AND PREVENTION FOR EXAMPLE, ARRHYTHMIA, VARIOUS NEURALGIAS AND ANALGESIC | EISAI CO., LTD. (JP) | 2004-08-31 | — | — | US | disclosed |
| EP-1254904-A1 | NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-11-06 | — | — | EP | disclosed |