Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873813 | 0.86 | ADK (0.43) | GSK3BADK | |
| SCHEMBL3877450 | 0.86 | ADK (0.43) | GSK3BADK | |
| SCHEMBL6879951 | 0.84 | XDH (0.42) | XDHGSK3BSMN1; SMN2TMIGD3HTR2C | |
| SCHEMBL6882325 | 0.80 | XDH (0.46) | XDHSMN1; SMN2TMIGD3HTR2CHTR2B | |
| SCHEMBL9805128 | 0.79 | GSK3B (0.49) | GSK3BADK | |
| SCHEMBL6752564 | 0.78 | XDH (0.44) | XDHSMN1; SMN2TMIGD3HTR2CHTR2B | |
| SCHEMBL5472025 | 0.77 | CDK1 (0.42) | ADK | |
| SCHEMBL5474432 | 0.77 | CDK1 (0.42) | ADK | |
| SCHEMBL28542110 | 0.76 | GDA (0.48) | XDHGSK3B | |
| SCHEMBL28631534 | 0.76 | GDA (0.48) | XDHGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |