Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886938 | 0.84 | XDH (0.48) | XDHSMN1; SMN2GSK3BTMIGD3HTR2C | |
| SCHEMBL6885088 | 0.75 | GSK3B (0.36) | GSK3B | |
| SCHEMBL6884989 | 0.75 | GSK3B (0.36) | GSK3B | |
| SCHEMBL6885551 | 0.74 | GSK3B (0.36) | GSK3B | |
| SCHEMBL6887384 | 0.74 | GSK3B (0.36) | GSK3B | |
| SCHEMBL3877450 | 0.73 | ADK (0.43) | GSK3BPAX8 | |
| SCHEMBL2873813 | 0.73 | ADK (0.43) | GSK3BPAX8 | |
| SCHEMBL6884015 | 0.72 | GSK3B (0.35) | GSK3B | |
| SCHEMBL6885692 | 0.72 | ALDH1A1 (0.38) | GSK3B | |
| SCHEMBL6882294 | 0.72 | GSK3B (0.34) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |