Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.50 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880479 | 0.84 | KMT2A (0.52) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL12882191 | 0.83 | KMT2A (0.51) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL6880624 | 0.78 | KMT2A (0.46) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL5983023 | 0.76 | KMT2A (0.55) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL12882196 | 0.68 | KMT2A (0.48) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL28452609 | 0.68 | KMT2A (0.52) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL12883780 | 0.68 | DCK (0.42) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL5344718 | 0.67 | RAB9A (0.41) | KMT2AALDH1A1KDM4ETSHRNPC1 | |
| SCHEMBL7528356 | 0.67 | MAPK14 (0.45) | KMT2AALDH1A1NPC1RAB9ACNR2 | |
| SCHEMBL7527286 | 0.67 | PTGS2 (0.43) | KMT2AALDH1A1KLK7KLK14KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |