Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983023 | 0.76 | KMT2A (0.55) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL9335990 | 0.70 | CTRB1 (0.39) | KMT2AALDH1A1 | |
| SCHEMBL7528362 | 0.69 | ADORA3 (0.51) | KMT2AALDH1A1KDM4E | |
| SCHEMBL6886945 | 0.67 | KMT2A (0.50) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| Hydrochloric Acid SCHEMBL3655605 | 0.67 | MAPT (0.59) | PTGS2KMT2AALDH1A1POLBCA1 | |
| SCHEMBL1797197 | 0.67 | MAPT (0.59) | PTGS2KMT2AALDH1A1POLBCA1 | |
| SCHEMBL6880479 | 0.66 | KMT2A (0.52) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL12882191 | 0.65 | KMT2A (0.51) | KMT2AALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL2796671 | 0.64 | ALDH1A1 (0.67) | KMT2AALDH1A1HPGDPOLBCA1 | |
| Hydrochloric Acid SCHEMBL3246059 | 0.63 | LMNA (0.65) | KMT2AALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761681-B1 | Process for the preparation of substituted derivatives of N-ethylglycine | HOECHST AG (DE) | 2002-03-13 | — | — | EP | disclosed |