Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 9/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563032 | 0.87 | ALDH1A1 (0.37) | RAB9ATDP1NPC1L3MBTL1MAOB | |
| SCHEMBL6888756 | 0.83 | ALDH1A1 (0.35) | TDP1KDM4EMAPTHPGD | |
| SCHEMBL6882521 | 0.76 | PTGS2 (0.39) | TDP1KDM4EMAPT | |
| SCHEMBL6882523 | 0.76 | PTGS2 (0.39) | TDP1KDM4EMAPT | |
| SCHEMBL6884736 | 0.71 | ALOX5 (0.45) | MRGPRX4MAOBMAOA | |
| SCHEMBL6882582 | 0.71 | ALDH1A1 (0.34) | TDP1KDM4EMAPTHPGD | |
| SCHEMBL6888828 | 0.71 | FFAR1 (0.43) | — | |
| SCHEMBL21543853 | 0.69 | TDP1 (0.55) | RAB9ATDP1NPC1KDM4ECYP1A2 | |
| SCHEMBL6883547 | 0.69 | MAOB (0.43) | RAB9AALOX5APNPC1HSP90AA1MAOB | |
| SCHEMBL6889766 | 0.68 | MRGPRX4 (0.37) | RAB9ATDP1MRGPRX4ALOX5APNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |