Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307975 | 0.74 | MAPT (0.40) | KMT2AALDH1A1MAPTLMNAPOLB | |
| SCHEMBL6754862 | 0.73 | MAPK1 (0.46) | KMT2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL6553046 | 0.73 | HSD17B2 (0.56) | KMT2AMEN1KDM4EPOLBGAA | |
| SCHEMBL6887250 | 0.72 | ESR1 (0.48) | ESR1CA1CA2CA12CA7 | |
| SCHEMBL17907572 | 0.71 | NPC1 (0.42) | CA1CA2KMT2AMEN1NPC1 | |
| SCHEMBL8948561 | 0.71 | TPMT (0.38) | CA1CA2GAA | |
| SCHEMBL5983433 | 0.71 | GAA (0.31) | ESR1CA1CA2CA12CA7 | |
| SCHEMBL5047980 | 0.70 | LOXL2 (0.33) | KMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL9494580 | 0.70 | SLC7A5 (0.45) | CA1CA2CA12CA9CA14 | |
| SCHEMBL43876 | 0.69 | ALDH1A1 (0.49) | KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702887-A | BENZ(B)ACRIDINIUM-12-CARBOXYLATE COMPOUNDS | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-12-30 | — | — | US | claimed |
| EP-0754178-B1 | NOVEL FUNCTIONALIZED HYDROPHILIC ACRIDINIUM ESTERS | BAYER AG (US) | 2003-01-15 | — | — | EP | disclosed |
| EP-0617288-B1 | Long emission wavelength chemiluminescent compounds and their use in test assays | NOVARTIS AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| EP-0982298-A1 | Novel functionalized hydrophilic acridinium esters | Ciba Corning Diagnostics Corp. (US) | 2000-03-01 | — | — | EP | disclosed |
| US-5879894-A | DETECTION AND/OR QUANTITATION OF AT LEAST TWO SUBSTANCES IN A TEST SAMPLE; APPLICATION IN CLINICAL DIAGNOSTICS | CHIRON DIAGNOSTICS CORPORATION (US) | 1999-03-09 | — | — | US | disclosed |
| US-5702887-A | BENZ(B)ACRIDINIUM-12-CARBOXYLATE COMPOUNDS | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| US-5656426-A | USEFUL AS CHEMILUMINESCENT AGENT IN IMMUNOASSAY AND GENE PROBE ASSAY WITH IMPROVED SENSITIVITY | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0754178-A1 | NOVEL FUNCTIONALIZED HYDROPHILIC ACRIDINIUM ESTERS | Ciba Corning Diagnostics Corp. (US) | 1997-01-22 | — | — | EP | disclosed |
| WO-1995027702-A1 | NOVEL FUNCTIONALIZED HYDROPHILIC ACRIDINIUM ESTERS | CIBA CORNING DIAGNOSTICS CORP. (US) | 1995-10-19 | — | — | WO | disclosed |
| US-5395752-A | Detecting emission signals of conjugates of angular or linear four ring or three ring acridinium compounds | CIBA CORNING DIAGNOSTICS CORP. (US) | 1995-03-07 | — | — | US | disclosed |
| WO-1994021823-A1 | LONG EMISSION WAVELENGTH CHEMILUMINESCENT COMPOUNDS AND THEIR USE IN TEST ASSAYS | CIBA CORNING DIAGNOSTICS CORP. (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0617288-A2 | Long emission wavelength chemiluminescent compounds and their use in test assays | CIBA-GEIGY AG (CH) | 1994-09-28 | — | — | EP | disclosed |