Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 3/20 | 0.77 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CHKA | P35790 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014268 | 0.88 | TSHR (1.00) | ALDH1A1TSHRTAAR1SMN1; SMN2AOC3 | |
| SCHEMBL15900 | 0.88 | TSHR (1.00) | ALDH1A1TSHRTAAR1SMN1; SMN2AOC3 | |
| SCHEMBL24735547 | 0.88 | TSHR (1.00) | ALDH1A1TSHRTAAR1SMN1; SMN2AOC3 | |
| SCHEMBL27766437 | 0.88 | TSHR (1.00) | ALDH1A1TSHRTAAR1SMN1; SMN2AOC3 | |
| SCHEMBL22028494 | 0.86 | TSHR (0.77) | ALDH1A1TSHRTAAR1AOC3LMNA | |
| SCHEMBL12096794 | 0.86 | ALDH1A1 (0.63) | ALDH1A1TSHRTAAR1KMT2AMEN1 | |
| Bromide SCHEMBL414532 | 0.85 | TSHR (0.94) | ALDH1A1TSHRTAAR1SMN1; SMN2AOC3 | |
| Iodide SCHEMBL6672021 | 0.85 | TSHR (0.94) | ALDH1A1TSHRTAAR1SMN1; SMN2AOC3 | |
| Hydrochloric Acid SCHEMBL6391891 | 0.85 | TSHR (0.94) | ALDH1A1TSHRTAAR1SMN1; SMN2AOC3 | |
| SCHEMBL7911439 | 0.85 | TSHR (0.94) | ALDH1A1TSHRTAAR1SMN1; SMN2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771069-B1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | BAYER CROPSCIENCE AG (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-6730799-B2 | O-HYDROXYETHYL-O'-METHYL-BENZOFURANDIONE DIOXIMES ARE REARRANGED IN THE PRESENCE OF A DILUENT AND IN THE PRESENCE OF AN ACID OR A BASE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-04 | — | — | US | disclosed |
| US-20020169316-A1 | Process for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-14 | — | — | US | disclosed |
| US-4897105-A | (1,2,4)-THIADIAZOLO(2,3-A)PYRIMIDINE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0239064-A2 | Herbicidal compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-30 | — | — | EP | disclosed |
| EP-0023841-B1 | 5 PYRIMIDINOL PHOSPHORUS ESTERS, AND METHODS FOR THEIR MANUFACTURE, COMPOSITIONS CONTAINING THOSE ESTERS AND THEIR USE AS PESTICIDES | THE DOW CHEMICAL COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169316-A1 | Process for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines | CYP4Z1, CYP4X1, CYP51A1 | ALDH1A1 131/4885TSHR 4258/4885TAAR1 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.