SCHEMBL6887705

SCHEMBL6887705

CCOC(C)OCC.O=CC(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11341801 0.81 LMNA (0.57) LMNATHRB
SCHEMBL4293299 0.79 LMNA (0.71) LMNATHRB
Acetaldehyde SCHEMBL212729 0.79 LMNA (0.71) LMNATHRB
SCHEMBL11079148 0.79 LMNA (0.55) LMNATHRB
SCHEMBL401436 0.78 LMNA (0.60) LMNATHRB
Propionaldehyde SCHEMBL1523503 0.77 LMNA (0.67) LMNATHRB
Formic Acid SCHEMBL6366884 0.77 LMNA (0.67) LMNATHRB
Formamide SCHEMBL856006 0.77 LMNA (0.67) LMNATHRB
Isobutyraldehyde SCHEMBL427264 0.77 LMNA (0.67) LMNATHRB
SCHEMBL9789571 0.76 LMNA (0.57) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6794492-B2 N-(2,2,2-TRIFLUOROETHYL)GLYCINE DERIVATIVES; CAN BE USED TO PREPARE LIPOPHILIC PROTEINS ADAPTED FOR CROSSING THE BLOOD BRAIN BARRIER CLEMSON UNIVERSITY 2004-09-21 US disclosed
US-20010046960-A1 Novel perfluoroalkyl compounds and their methods of use and manufacture CLEMSON UNIVERSITY 2001-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010046960-A1 Novel perfluoroalkyl compounds and their methods of use and manufacture PFAS, PTMS, QRFPR LMNA 4284/4885THRB 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.