SCHEMBL6889087

SCHEMBL6889087

CCCCOC(C)c1c(C(=O)O)cccc1N(C)C

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 3/20 0.40
TSHR P16473 5/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
PTPN11 Q06124 2/20 0.38
PLK1 P53350 1/20 0.38
TP53 P04637 2/20 0.37
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PLA2G4B P0C869 1/20 0.36
CA12 O43570 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17797796 0.82 TSHR (0.45) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL6889095 0.80 KDM4E (0.40) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL2221402 0.76 ALDH1A1 (0.48) KDM4EALDH1A1TSHRTDP1L3MBTL1
SCHEMBL9903580 0.75 ALDH1A1 (0.43) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL18575525 0.75 MEN1 (0.49) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL9011052 0.75 SLC37A4 (0.45) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL17797928 0.74 TSHR (0.38) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL1024830 0.73 TSHR (0.47) KDM4EMEN1KMT2AALDH1A1TSHR
SCHEMBL4882921 0.72 ALDH1A1 (0.41) KDM4EMEN1KMT2AALDH1A1TSHR
SCHEMBL17797804 0.71 TSHR (0.41) KDM4EMEN1RECQLKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1241959-B1 Use of soak-off radiation curable nail coatings CREATIVE NAIL DESIGN INC (US) 2013-09-11 EP disclosed
US-6803394-B2 ACRYLATED POLYURETHANE; PROTECTIVE COATINGS GEL PRODUCTS, INC. 2004-10-12 US disclosed
US-20030073753-A1 Radiation curable nail coatings and artificial nail tips and methods of using same JEFFERIES FINANCE LLC, AS COLLATERAL AGENT 2003-04-17 US disclosed