SCHEMBL6889095

SCHEMBL6889095

CCCCOC(C)c1cccc(C(=O)O)c1N(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 2/20 0.40
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
PTPN11 Q06124 1/20 0.38
PLK1 P53350 1/20 0.38
GBA1 P04062 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
PLA2G4B P0C869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18575525 0.84 MEN1 (0.49) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL9011052 0.83 SLC37A4 (0.45) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL6889087 0.80 KDM4E (0.40) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL10448913 0.79 ALDH1A1 (0.52) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL4882921 0.77 ALDH1A1 (0.41) KDM4EMEN1KMT2AALDH1A1TSHR
SCHEMBL2221408 0.76 LMNA (0.41) KDM4EMEN1KMT2AALDH1A1TSHR
SCHEMBL27173937 0.75 ALDH1A1 (0.43) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL21753741 0.75 TSHR (0.47) KDM4EALDH1A1TSHRTDP1L3MBTL1
SCHEMBL28968650 0.74 MEN1 (0.45) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL17797796 0.73 TSHR (0.45) KDM4EMEN1RECQLKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136337-A1 DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER クラレノリタケデンタル株式会社 2023-07-20 WO disclosed
EP-1241959-B1 Use of soak-off radiation curable nail coatings CREATIVE NAIL DESIGN INC (US) 2013-09-11 EP disclosed
US-6803394-B2 ACRYLATED POLYURETHANE; PROTECTIVE COATINGS GEL PRODUCTS, INC. 2004-10-12 US disclosed
US-20030073753-A1 Radiation curable nail coatings and artificial nail tips and methods of using same JEFFERIES FINANCE LLC, AS COLLATERAL AGENT 2003-04-17 US disclosed
US-6288138-B1 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 2001-09-11 US disclosed