Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889106 | 0.93 | L3MBTL1 (0.33) | L3MBTL1ALDH1A1KMT2AMAPK1TDP1 | |
| SCHEMBL6301520 | 0.93 | L3MBTL1 (0.33) | L3MBTL1ALDH1A1KMT2AMAPK1TDP1 | |
| SCHEMBL137087 | 0.88 | PTPN1 (0.30) | — | |
| SCHEMBL3239947 | 0.87 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL10037957 | 0.87 | S1PR3 (0.32) | — | |
| SCHEMBL10090479 | 0.87 | ALDH1A1 (0.35) | L3MBTL1ALDH1A1KMT2AMAPK1TDP1 | |
| SCHEMBL6301516 | 0.86 | L3MBTL1 (0.33) | L3MBTL1ALDH1A1KMT2AMAPK1TDP1 | |
| SCHEMBL8116380 | 0.85 | PTPN1 (0.33) | — | |
| SCHEMBL1656937 | 0.84 | ADRB2 (0.33) | ALDH1A1MAPK1ADRB2HTR1A | |
| SCHEMBL559885 | 0.83 | ADRB2 (0.33) | ALDH1A1ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174045-B2 | Benzopyrylium compounds | PIERCE BIOTECHNOLOGY, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180002340-A1 | BENZOPYRYLIUM COMPOUNDS | PIERCE BIOTECHNOLOGY, INC. | 2018-01-04 | — | — | US | disclosed |
| US-9676787-B2 | Benzopyrylium compounds | PIERCE BIOTECHNOLOGY, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-9676787-B2 | Benzopyrylium compounds | PIERCE BIOTECHNOLOGY, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20170152267-A9 | BENZOPYRYLIUM COMPOUNDS | DYOMICS GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20170152267-A9 | BENZOPYRYLIUM COMPOUNDS | DYOMICS GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20150322078-A1 | BENZOPYRYLIUM COMPOUNDS | DYOMICS GMBH (DE) | 2015-11-12 | — | — | US | disclosed |
| US-20150322078-A1 | BENZOPYRYLIUM COMPOUNDS | DYOMICS GMBH (DE) | 2015-11-12 | — | — | US | disclosed |
| EP-1428858-B1 | Hydrophilic marker dyes based on benzopyrylo-polymethines | DYOMICS GMBH (DE) | 2013-01-30 | — | — | EP | disclosed |
| EP-1428858-B1 | Hydrophilic marker dyes based on benzopyrylo-polymethines | DYOMICS GMBH (DE) | 2013-01-30 | — | — | EP | disclosed |
| EP-1428858-A1 | Hydrophilic marker dyes based on benzopyrylo-polymethines | Dyomics GmbH (DE) | 2004-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152267-A9 | BENZOPYRYLIUM COMPOUNDS | PABPC4, SSBP1, RBBP5 | L3MBTL1 332/4885ALDH1A1 3082/4885KMT2A 3196/4885 |
| US-20150322078-A1 | BENZOPYRYLIUM COMPOUNDS | PABPC4, SSBP1, RBBP5 | L3MBTL1 332/4885ALDH1A1 3082/4885KMT2A 3196/4885 |
| US-10174045-B2 | Benzopyrylium compounds | PABPC4, SSBP1, RBBP5 | L3MBTL1 332/4885ALDH1A1 3082/4885KMT2A 3196/4885 |
| US-20180002340-A1 | BENZOPYRYLIUM COMPOUNDS | PABPC4, SSBP1, RBBP5 | L3MBTL1 332/4885ALDH1A1 3082/4885KMT2A 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.