Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889190 | 1.00 | TSHR (0.33) | TSHRRNPEPSLC7A5MMP1MMP2 | |
| SCHEMBL6889194 | 1.00 | TSHR (0.33) | TSHRRNPEPSLC7A5MMP1MMP2 | |
| SCHEMBL15290584 | 0.81 | TSHR (0.38) | TSHRRNPEPSLC7A5MMP1MMP2 | |
| SCHEMBL4368789 | 0.81 | TSHR (0.38) | TSHRRNPEPSLC7A5MMP1MMP2 | |
| SCHEMBL181415 | 0.81 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL4377419 | 0.80 | LMNA (0.48) | TP53 | |
| SCHEMBL6889186 | 0.80 | LMNA (0.48) | TP53 | |
| SCHEMBL6889182 | 0.80 | LMNA (0.48) | TP53 | |
| SCHEMBL10633540 | 0.78 | LMNA (0.46) | TP53 | |
| SCHEMBL28938350 | 0.77 | LMNA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720463-B1 | REDUCING AN ALKYLHYDROXYESTER WITH EASY TO HANDLE SODIUM BOROHYDRIDE; MAINTAINING OPTICAL ACTIVITY | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| EP-1146032-A1 | PROCESS FOR THE PRODUCTION OF ALKANEDIOL DERIVATIVES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-10-17 | — | — | EP | disclosed |