SCHEMBL6889303

SCHEMBL6889303

OC(Cc1ccccc1)C1CCCN1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.52
SLC6A4 P31645 3/20 0.52
SLC6A3 Q01959 3/20 0.52
CTSC P53634 1/20 0.45
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25339415 1.00 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3CTSCPOLB
SCHEMBL22260324 1.00 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3CTSCPOLB
SCHEMBL22461896 1.00 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3CTSCPOLB
SCHEMBL20833040 1.00 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3CTSCPOLB
SCHEMBL7245886 0.95 SLC6A2 (0.58) SLC6A2SLC6A4SLC6A3POLB
SCHEMBL22461859 0.85 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3CTSC
SCHEMBL25968627 0.84 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3POLB
SCHEMBL27682387 0.84 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3POLB
SCHEMBL20833299 0.84 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3POLB
SCHEMBL22461861 0.84 SLC6A2 (0.53) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD (SG) 2026-02-26 US disclosed
US-12428442-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2025-09-30 US disclosed
US-20240174710-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2024-05-30 US disclosed
US-11718638-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2023-08-08 US disclosed
US-20220356204-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2022-11-10 US disclosed
WO-2020191252-A1 TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2020-09-24 WO disclosed
CN-111051281-A Compounds, compositions and methods for synthesis 波涛生命科学有限公司 2020-04-21 CN disclosed
WO-2019055951-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2019-03-21 WO disclosed
EP-1379510-A1 ARYL AND HETEROARYL UREA CHK1 INHIBITORS FOR USE AS RADIOSENSITIZERS AND CHAMOSENSITIZERS ICOS CORPORATION (US) 2004-01-14 EP disclosed
WO-2002070494-A1 ARYL AND HETEROARYL UREA CHK1 INHIBITORS FOR USE AS RADIOSENSITIZERS AND CHAMOSENSITIZERS ICOS CORPORATION (US) 2002-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718638-B2 Compounds, compositions and methods for synthesis ALKBH1, DUT, RNGTT SLC6A2 2493/4885SLC6A4 1561/4885SLC6A3 3086/4885
US-20220356204-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS ALKBH1, DUT, RNGTT SLC6A2 2493/4885SLC6A4 1561/4885SLC6A3 3086/4885
US-12428442-B2 Compounds, compositions and methods for synthesis ALKBH1, DUT, RNGTT SLC6A2 2493/4885SLC6A4 1561/4885SLC6A3 3086/4885
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS NSUN2, NSUN3, NOP2 SLC6A2 1858/4885SLC6A4 1829/4885SLC6A3 2491/4885
US-20240174710-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS ALKBH1, DUT, RNGTT SLC6A2 2493/4885SLC6A4 1561/4885SLC6A3 3086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.