SCHEMBL6889498

SCHEMBL6889498

CC1=C([Zr+](Cc2ccccc2)C2=C(C)C=CC2)CC=C1.CC[O-]

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.31
CA12 O43570 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
ATM Q13315 1/20 0.30
CA9 Q16790 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6355210 0.71 TP53 (0.33) TP53
SCHEMBL4576256 0.61 MAOA (0.36) ATM
Hydrochloric Acid SCHEMBL617893 0.61 KDM4E (0.32) TP53
SCHEMBL818775 0.61 TP53 (0.32) TP53
Toluene SCHEMBL11600656 0.60 ACHE (0.50) LMNAPOLB
SCHEMBL28805987 0.60 KDM4E (0.31) TP53CYP3A4LMNAPOLB
SCHEMBL1135095 0.60 TP53 (0.31) TP53LMNAPOLB
SCHEMBL7751963 0.60 TP53 (0.31) TP53LMNAPOLB
SCHEMBL7032648 0.60 MAOA (0.36) ATM
Toluene SCHEMBL9066303 0.60 ACHE (0.65) TP53CA12CYP1A2CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040014917-A1 Catalyst support, production and use thereof in the polymerization of olefins MERCK PATENT GMBH (DE) 2004-01-22 US disclosed