SCHEMBL6889554

SCHEMBL6889554

CC(O)(O)c1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
HNF4A P41235 1/20 0.39
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 2/20 0.39
HPGD P15428 1/20 0.39
BCL2L1 Q07817 1/20 0.39
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
PTPN5 P54829 1/20 0.36
PDE4B Q07343 3/20 0.36
PDE4A P27815 2/20 0.36
PDE4C Q08493 2/20 0.36
PDE4D Q08499 2/20 0.36
PLK1 P53350 1/20 0.36
BACE1 P56817 1/20 0.35
ENPP1 P22413 1/20 0.35
CYP2A6 P11509 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27781320 0.84 CA2 (0.41) PDCD1CD274HNF4AALDH1A1HSD17B10
Hydrogen Sulfide SCHEMBL27603612 0.82 CA2 (0.40) PDCD1CD274HNF4AALDH1A1HSD17B10
SCHEMBL28383421 0.80 HNF4A (0.43) PDCD1CD274HNF4AALDH1A1HSD17B10
SCHEMBL6888191 0.79 HNF4A (0.38) PDCD1CD274HNF4AALDH1A1HSD17B10
Phosphoric Acid SCHEMBL28381125 0.79 PTPN5 (0.51) PDCD1CD274HNF4AALDH1A1HDAC4
SCHEMBL28874153 0.79 PDE4A (0.46) HNF4AALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL985288 0.79 ALDH1A1 (0.47) PDCD1CD274HNF4AALDH1A1HSD17B10
SCHEMBL9695975 0.78 PDCD1 (0.37) PDCD1CD274HNF4AALDH1A1HSD17B10
SCHEMBL29854235 0.77 HNF4A (0.47) PDCD1CD274HNF4AALDH1A1HSD17B10
Methyl Alcohol SCHEMBL27488232 0.77 ALDH1A1 (0.50) PDCD1CD274HNF4AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112368136-B Improved forming device for casting an optical product with a thin sheet on top, corresponding method, and optical product 依视路国际公司 2022-07-29 CN disclosed
CN-112888973-A Improved optical articles comprising optical elements and methods of making the same 依视路国际公司 2021-06-01 CN disclosed
CN-112368136-A Improved forming device for casting an optical product with a thin sheet on top, corresponding method, and optical product 依视路国际公司 2021-02-12 CN disclosed
CN-1209236-C Polarizing moulded goods and its making method YAMAMOTO KAGAKU K K (JP) 2005-07-06 CN disclosed
WO-2004113956-A2 PHOTOCHROMIC PLATE CONTAINING MELANIN VISION-EASE LENS, INC. (US) 2004-12-29 WO disclosed
CN-1367077-A Polarizing moulded goods and its making method YAMAMOTO KAGAKU K K (JP) 2002-09-04 CN disclosed