Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308933 | 0.86 | LMNA (0.62) | LMNAKMT2AMEN1KDM4ECRHBP | |
| SCHEMBL29418226 | 0.84 | LMNA (0.74) | LMNAKMT2AMEN1GAAMAPT | |
| SCHEMBL819332 | 0.84 | LMNA (0.74) | LMNAKMT2AMEN1GAAMAPT | |
| SCHEMBL14775358 | 0.83 | LMNA (0.54) | LMNAKMT2AMEN1KDM4ECRHBP | |
| SCHEMBL16675180 | 0.80 | LMNA (0.69) | LMNAKMT2AMEN1GAAMAPT | |
| SCHEMBL14151440 | 0.80 | KMT2A (0.64) | LMNAKMT2AMEN1KDM4ECRHBP | |
| SCHEMBL410350 | 0.79 | LMNA (0.67) | LMNAKMT2AMEN1GAAMAPT | |
| SCHEMBL7176954 | 0.79 | LMNA (0.67) | LMNAKMT2AMEN1GAAMAPT | |
| SCHEMBL11303983 | 0.78 | LMNA (0.53) | LMNAKMT2AMEN1KDM4ECRHBP | |
| SCHEMBL304537 | 0.78 | MAPT (0.43) | KMT2AMEN1KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |